Progression and cardiovascular outcomes of chronic kidney disease in a community: a pharmacoepidemiologic perspective

We plan to follow up the rural population screened nine years back as part of Screening and Early Evaluation of Kidney Disease (SEEK) project. Ours was a community-based study, where the investigator did house to house survey as compared to SEEK project which was camp-based done elsewhere. This population continues to be rural based and is under the field practice area of our community medicine department. We expect to be able to follow them up with previously available identifiers. We found a prevalence of CKD of about 32.1 % and identified patients were requested to visit a tertiary care set up but follow up was poor as most were asymptomatic. We plan to study the progression in those identified to have CKD with cardiovascular outcomes and identify new cases if any of those who did not have CKD earlier. The prevalence of the risk factors of CKD is increasing in the South Asian population, this adds for the increased prevalence of CKD in these population. South Asian population face a higher burden of CKD and cardiovascular disease. There is paucity of data on the progression and cardiovascular outcomes of CKD in Indian setup. This is a prospective cohort study which will be conducted for 12 months. Consequence of this study is of great benefit to the community.  It would help to sensitize the public and healthcare professionals regarding the impact of CKD on public health and may help in the formulation of preventive health policies and allotment of reliable resources for the treatment of this disease, which is crucial in India. It would also aid in strengthening the validity of MDRD formula in India.