NCT01926301撤回不适用
Cerebrovascular Autoregulation in Patients With Severe Sepsis and Septic Shock, Influence of Renal Replacement Therapy
Johannes Gutenberg University Mainz1 个研究点 分布在 1 个国家开始时间: 2013年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Cerebrovascular autoregulation
研究概览
简要总结
The cerebrovascular autoregulation is impaired in patients with severe sepsis and septic shock. A continuous veno-venous hemodialysis may improve impaired cerebrovascular autoregulation.
Hypothesis: continuous hemodialysis recovers impaired cerebrovascular autoregulation in patients with acute severe sepsis and septic shock.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •severe sepsis or septic shock
- •adult patients
- •possibility of transcranial Doppler ultrasound
排除标准
- •traumatic brain injury
- •known cerebrovascular diseases
- •Infection of the brain
- •chronic renal failure
- •pregnancy
结局指标
主要结局
Cerebrovascular autoregulation
时间窗: during the first 4 days
Cerebrovascular autoregulation measured daily at the first 4 days of severe sepsis and septic shock
次要结局
- Delirium(at day 4)
研究者
Patrick Schramm
Associate Professor
Johannes Gutenberg University Mainz
研究点 (1)
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