Study of Association Between Digital Osteoarthritis and Lower Limb Osteoarthritis
- Conditions
- Digital Arthrosis
- Interventions
- Radiation: Hand X-rays
- Registration Number
- NCT01805349
- Lead Sponsor
- Centre Hospitalier Universitaire de Nice
- Brief Summary
Among the risk factors for lower limb osteoarthritis, if obesity is probably the most studied, digital osteoarthritis received increasing interest in recent years. Recent publications have highlighted a link between obesity and digital osteoarthritis, but also a very probable link between digital osteoarthritis and structural progression of knee osteoarthritis. Few data including hip exist and need to be confirmed on larger scale studies. We have with "Khoala" a national multiregional cohort of symptomatic gonarthrosis and coxarthrosis representative of the general population (which is rarely the case in the literature) including X ray, clinical and biological follow-up (hips and / or knees).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 479
- men or women aged 40 to 75 years
- with symptomatic osteoarthritis of the hip and / or knee (femoro-tibial), unilateral or bilateral
- with a confirmed diagnosis (criteria of the American College of Rheumatology :ACR) and Kellgren and Lawrence radiological stage ≥ 2.
- painful hip or knee prosthesis
- osteotomy in the past
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description X-Rays Hand X-rays patients with digital arthrosis and hip/knee arthrosis will practice hand X-rays
- Primary Outcome Measures
Name Time Method Kellgren and Lawrence score Change at 2 years Kellgren and Lawrence score for hip or knee
- Secondary Outcome Measures
Name Time Method Harris score Harris score at 2 years
Trial Locations
- Locations (1)
Department of rheumatology, nice university hospital
🇫🇷Nice, France