Thorax injury in relation with systemic neutrophil activatio

Completed

• Conditions: Trauma, immuunsysteem en longaandoeningen; Acute respiratory distress syndrome; ARDS; Pulmonary failure

• Registration Number: NL-OMON31401
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Thorax trauma (AIS > 2)
Age 18 - 70

Exclusion Criteria

Additional trauma (AIS > 2)
Immunological compromized (corticosteroids, chemotherapy)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary parameter: Activation of neutrophils (receptor profiles) and local<br /><br>injury<br /><br>Primary endpoint: Development of ARDS</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints:<br /><br><br /><br>Trauma severity (HTTSS / NISS / Blood gas on admission)<br /><br>Difference between penetrating and blunt trauma </p><br>