A randomized controlled clinical trial to evaluate the efficacy of three rotary instruments in reducing microbial load of infected root canals.

Not yet recruiting

Conditions: Infected root canals(asymptomatic apical periodontitis)

Registration Number: CTRI/2019/04/018540

Lead Sponsor: riluwan siddique

Brief Summary: One of the major goals of the treatment of infected root canals of teeth with apical periodontitis is to promote maximal reduction in intracanal bacterial population.ProTaper Next was developed as the successor of the ProTaper Universal system.The Protaper next system was as effective as Protaper Universal and WaveOne in the removal of bacteria during root canal treatment.Recently introduced ProTaper Gold was found to produce less transportation compared to ProTaper Universal . XP-endo Shaper (XP) was introduced in 2015 and boasts of new rotary NiTi snake-shaped instrument developed with MaxWire technology. It has been proved that the XP Endoshaper follows the root canal anatomy of oval shaped canals by preparing and touching more walls than the Vortex Blue system.Till date no study has related to antimicrobial efficacy regarding ProTaper Next,ProTaper Gold and XP Endoshaper in clinical trials. Therefore aim of this randomized controlled clinical trial was to compare the microbial load reduction of ProTaper Next, ProTaper Gold and XP Endoshaper in infected root canals of teeth with asymptomatic apical periodontitis. The null hypothesis was that there was no statistically significant difference in microbial load reduction between three rotary systems.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

: asymptomatic apical periodontitis, single & multi-rooted teeth with straight canals, intact pulp chamber walls, necrotic pulps confirmed by pulp tests and, clinical and radiographic evidence of asymptomatic apical periodontitis.

Exclusion Criteria

Teeth with gross carious lesion, crown or root fracture, retreatment, periodontal pocket deeper than 4mm were excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in microbial load was evaluated using real time polymerase chain reaction	Samples were collected from infected root canals on same day of treatment procedure. No follow up samples collected \| Samples collected before instrumentation(S1 samples) \| Samples collected after instrumentation (S2 samples)

Secondary Outcome Measures

Name	Time	Method
Reduction in microbial load was evaluated using real time polymerase chain reaction.	Samples were collected from infected root canals on same day of treatment procedure. No follow up samples collected

Trial Locations

Locations (1): Saveetha dental college
🇮🇳
Chennai, TAMIL NADU, India
Saveetha dental college
🇮🇳Chennai, TAMIL NADU, India
Riluwan siddique
Principal investigator
09743056316
riluwanas@gmail.com