HIT-CF Organoid Study: Stratifying Cystic Fibrosis Patients Based on Intestinal Organoid Response To Different CFTR-modulators
Recruiting
- Conditions
- Cystic Fibrosis CF
- Registration Number
- NL-OMON24027
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
–Male or female with confirmed diagnosis of CF
–Adult age on the date of informed consent
Exclusion Criteria
–Subject has at least one of the following CFTR-mutations:
•F508del, G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, S549R, R117H, A455E, 3849+10kbC>T
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intestinal organoid response of 500 subjects to three drug products of <br>different pharmaceutical companies, ranked by best response per drug product.
- Secondary Outcome Measures
Name Time Method ot applicable