NCT04374591Unknown不适用
The Role of Sodium Bicarbonate as Adjuvant Treatment of Computed Tomography Identified COVID-19 Pneumonia: A Preliminary Report of Short Term Follow up
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Time to clinical recovery
研究概览
简要总结
To report the possible role of S.B 8.4% in the treatment of COVID-19pneumonia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years.
- •Fever ≥ 38º C with upper respiratory tract manifestations, generalized bone ache with or without gastrointestinal symptoms as diarrhea.
- •Chest CT with signs suggestive of COVID-
- •Mild and moderate cases of COVID-19 pneumonia with respiratory and hemodynamic stability. - High C reactive protein (CRP).- With or without history of contact with index case who is isolated in a governmental hospital assigned for treatment of patients proved to have RT-PCR positive test for COVID-19
- •With or without abnormalities in the total or differential white cell count.
- •Welling to sign a fully informed consent.
排除标准
- •Severe and critical illness with respiratory failure and/ or hemodynamic instability.
- •CT with pleural effusion with or without lung cavitation.
- •Other organ failure.
研究组 & 干预措施
Sodium Bicarbonate
Other
Inhalation of Sodium Bicarbonate 8.4% via nebulizer
干预措施: Sodium Bicarbonate (Drug)
Control
Placebo Comparator
placebo
干预措施: Sodium Bicarbonate (Drug)
结局指标
主要结局
Time to clinical recovery
时间窗: 7 days
defined as return of body temperature and relief of cough for more than 72 hours measured in days
次要结局
- Pulmonary recovery status(7 days)
研究者
研究点 (1)
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