The effects of ceasing opioid, benzodiazepine, or Z-hypnotic drug use on measures of driving performance and postural balance.

Phase 4

Completed

• Conditions: Pijnklachten; chronic pain; Insomnia; 10040998; 10002861

• Registration Number: NL-OMON44190
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 94

Inclusion Criteria

Possession of a valid driver's license for at least 3 years.
A driving frequency of at least once a week.
A weekly driving distance of at least 50km.
Being able to operate a manual transmission
The chronic (at least 90 days per year) use of a relevant medication (for patients only).

Exclusion Criteria

Mini Mental State Examination score of less than 24.
Deemed medically unfit to drive based on a medical screening.
Recurrent illicit or recreational drug use.
Excessive alcohol use (>21 beverages per week)
Not willing to consider discontinuation of the use of a medication of interest in case this is advised by a clinician (patients only).
The use of any psychoactive substance (control participants only)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main outcome parameter of the study will be the standard deviation of the<br /><br>lateral position (SDLP) of the test vehicle during a standardized on-the-road<br /><br>driving test. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Furthermore, a neurocognitive test battery consisting of neuropsychological<br /><br>tests and laboratory computer tasks will be used. Also, a driving simulator<br /><br>test will be included. For our secondary objective, a postural balance task is<br /><br>included which measures body sway.</p><br>