Study for the effect on blood pressure and heart rate fluctuation by switching from DPP-4 inhibitor to SGLT2 inhibitor Luseogliflozin in patients with type 2 diabetes. - multicenter, prospective, randomized, open-label, parallel group, comparison study
Phase 4
- Conditions
- Type 2 diabetes mellitus
- Registration Number
- JPRN-UMIN000031451
- Lead Sponsor
- Hokkaido University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with taking SGLT2 inhibitors. 2) Hypersensitivity to Luseogliflozin. 3) Uncontrolled diabetic retinopathy 4) Severe liver dysfunction, renal dysfunction, or heart failure 5) Pregnancy, nursing woman or possibly pregnant woman 6) Severe diabetic ketosis, diabetic coma 7) Severe infection, pre and post operation , severe trauma 8) Deficiency of insulin secretion 9) BMI < 22kg/m2 10) eGFR < 30 ml/min 11) Patients with uncontrolled diet therapy. 12) Patients with irregular circadian rhythm. 13) Patients who thought to be inappropriate to enter this study for some reasons by physician's judgments
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method