Comparing Two Different Regional Anaesthetic Techniques With Standard IV Analgesic Technique For Post-Operative Pain Management In Patients Undergoing Laproscopic Cholecystectomy.

Completed

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/03/050416

Lead Sponsor: ABHINAV NANDA

Brief Summary: This study is a randomized,controlled, parallel group, single centre trial comparing the analgesicefficacy of ultrasound guided erector spinae plane block and transversus abdominisplane block for post-operative analgesia in patients undergoing laproscopiccholecystectomy. The study will be conducted over 18 months in 111patients in Subharti Medical College,Meerut, UP India. The primary outcomemeasures will be to evaluate and compare pain intensity after erector spinaeplane block and transversus abdominis plane block and compare it with standard IV analgesic techniqueand to evaluate and compare the time of first analgesic demand(hours) and the total amount of rescue analgesic consumption duringthe first 24 hours of postoperative period. The secondary outcomes willbe to compare overall patient satisfaction score and to compare hemodynamic changesamong the three groups.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 111

Inclusion Criteria

ASA physical status I-II.

Exclusion Criteria

1.Allergy to the study drug 2.Bleeding disorders 3.Inability to visualize the plane on USG 4.Patient using chronic analgesic medication 5.Psychiatric disorder 6.Contraindication to regional anaesthesia 7.Patient refusal 8.Cardiorespiratory disorder (e.g bronchial asthma,bradyarrythmias,heart 9.Block, CAD) 10.Hepatic , renal and neurological disease 11.Emergency operation.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To evaluate and compare pain intensity after erector spinae plane block and transversus abdominis plane block.	Assessment was done using NRS both at rest and on movement immediately and then at 15 min, 30 min, 45 min, 60 min, second hour, fourth hour, sixth hour, eighth hour, tenth hour,12th hour, and 24th hours postoperative.
Assessment of pain was done using NRS score.	Assessment was done using NRS both at rest and on movement immediately and then at 15 min, 30 min, 45 min, 60 min, second hour, fourth hour, sixth hour, eighth hour, tenth hour,12th hour, and 24th hours postoperative.
2.To evaluate and compare the time of first analgesic demand (hours) and the total amount of rescue analgesic consumption during the first 24 hours of postoperative period.	Assessment was done using NRS both at rest and on movement immediately and then at 15 min, 30 min, 45 min, 60 min, second hour, fourth hour, sixth hour, eighth hour, tenth hour,12th hour, and 24th hours postoperative.

Secondary Outcome Measures

Name	Time	Method
2.To compare hemodynamic changes among the three groups.
1.To compare overall patient satisfaction score using likert verbal rating score among the three groups.

Trial Locations

Locations (1): Subharti Medical College and Hospital
🇮🇳
Meerut, UTTAR PRADESH, India
Subharti Medical College and Hospital
🇮🇳Meerut, UTTAR PRADESH, India
Abhinav Nanda
Principal investigator
9780848998
drabhinavnanda@gmail.com