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Effect of Dual-Task Training and Cognitive Rehabilitation in Individuals With Multiple Sclerosis.

Not Applicable
Recruiting
Conditions
Multiple Sclerosis
Registration Number
NCT06949696
Lead Sponsor
Toros University
Brief Summary

The purpose of this study is to examine the effects of dual-task training and cognitive rehabilitation on gait, balance, fatigue and cognitive performance in individuals with multiple sclerosis.

Detailed Description

Multiple sclerosis (MS) is a complex disease characterized by chronic, inflammatory, demyelinating and neurodegenerative processes of the central nervous system (CNS) with heterogeneous clinical symptoms. Balance, gait and cognitive impairment are among the biggest problems in individuals with MS and significantly affect their daily lives.

Dual Task (DT); is the process of performing two tasks that can be performed independently and have different purposes simultaneously. Walking with dual tasks has recently been shown to resemble typical walking performance in daily life, thus providing clinicians with a realistic walking performance measurement in daily life. Although the effects of dual task performance in various neurological diseases have been partially described in the literature, the comparison of dual task training and cognitive rehabilitation on walking, balance, fatigue and cognitive performance has not been made and due to this deficiency in the literature, our study was planned and has originality. The aim of our study is to investigate the effects of dual task training and cognitive rehabilitation on walking, balance, fatigue and cognitive performance in individuals with MS.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Definite MS diagnosis by a neurologist
  • Can walk independently
  • Expanded Disability Status Scale (EDSS) score below 5
  • Has not had an attack in the last 3 months, has been medically stable for 6 months
  • Has not received a regular physiotherapy program in the last 6 months volunteer
Exclusion Criteria
  • Scoring 26 or below on the Montreal Cognitive Assessment Scale (MoCA)
  • Having systemic, orthopedic and neurological problems that may affect walking and balance in the assessments
  • Having additional psychiatric disorders

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Dynamic Gait Index (DGI)a year

DGI is a test that measures the capacity to adapt to changes in walking.It evaluates a total of 8 parameters over 24 points. Values of 19 points and below define the presence of a fall risk.

Secondary Outcome Measures
NameTimeMethod
Timed 25 Food Walk Test (T25FWT)a year

Timed 25 Food Walk Test is a test that evaluates walking speed. In the test, the patient is asked to walk 25 steps as quickly and safely as possible and the time is recorded in seconds with the average of 2 trials.

The 12-item MS Walking Scale (12-MSWS)a year

The 12-item MS Walking Scale (12-MSWS) that evaluates walking ability over the last 2 weeks, scaled from 0 to 100.

BICAMS (Brief International Cognitive Assessment for MS)a year

BICAMS (Brief International Cognitive Assessment for MS) is an international initiative to recommend and support a cognitive assessment that is brief, practical and universal.

Trial Making Test (TMT)a year

Trial Making Test (TMT)is used to evaluate individuals' executive functions, visual-motor perception, visual scanning and attention speed, motor function, organization, and planning.

Modified Fatigue Impact Scale (MFIS)a year

It is a multidimensional self-report questionnaire consisting of 21 questions in total, which is frequently used in individuals with MS and evaluates subjective fatigue physically (9 items), cognitively (10 items) and psychosocially (2 items).

Trial Locations

Locations (1)

Mersin University

🇹🇷

Mersin, Turkey

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