Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion

Phase 4

• Conditions: Second Trimester Abortion
• Interventions: Drug: Placebo; Drug: Mifepristone; Drug: Misoprostol

• Registration Number: NCT03044093
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion - a Double Blinded Randomized Controlled Trial

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01
• Study First Submitted: 2017-01-18
• Status Verified: 2017-02
• Study First Submitted QC: 2017-02-02
• Last Update Submitted: 2017-02-02
• Study First Posted: 2017-02-06
• Last Update Posted: 2017-02-06
• Primary Completion: 2019-01
• Study Completion: 2019-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• healthy
• no allergy known to these drugs
• second trimester abortion

Exclusion Criteria

• hematology diseases
• clotting factor deficiency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
MISOPROSTOL alone	Placebo	the common practice currently in our medical center for second trimester medical abortion/ Placebo
MISOPROSTOL alone	Misoprostol	the common practice currently in our medical center for second trimester medical abortion/ Placebo
Mifepristone and Misoprostol	Misoprostol	in addition to the common practice currently in our medical center for second trimester medical abortion we will add Mifepristone before administering Misoprostol. Mifepristone
Mifepristone and Misoprostol	Mifepristone	in addition to the common practice currently in our medical center for second trimester medical abortion we will add Mifepristone before administering Misoprostol. Mifepristone

Primary Outcome Measures

Name	Time	Method
Reduction in Hospital Stay Duration	Up to 24 months	number of days of hospital stay

Trial Locations

Locations (1)

Rambam Medical Campus; 🇮🇱 Haifa, Israel