Comparison of non-surgical periodontal treatment with and without adjunctive systemic antibiotics

Not Applicable

• Conditions: K05.3; K05.4; Chronic periodontitis; Periodontosis

• Registration Number: DRKS00028768
• Lead Sponsor: Poliklinik für Parodontologie,ZZMK (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt a.M.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-27
• Study Completion: 2022-06-30
• Results First Posted: 2023-01-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 425

Inclusion Criteria

Patients of the Dept. of Periodontology having received comprehensive periodontal treatment between January 2008 band December 2018;
- Results of microbiological testing of subgingival biofilm prior to treatment (T0);
- Complete periodontal examination prior to periodontal treatment (T0) and 6 weeks to 3 months thereafter (T1) including probing pocket depths (PPD) and vertical clinical attachment level (CAL-V) at 6 sites/tooth;
- Radiographs depicting the whole dentition at start of periodntal treatment (not older than 6 months at T0).

Exclusion Criteria

Incomplete or missing data (periodontal charts, radiographs and/or microbiological test reports)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Achievement of treat-to-target” endpoint, e.g. =4 sites with probing pocket depths =5 mm (Feres et al., 2020) 6 weeks to 3 months after SI (T1)

Secondary Outcome Measures

Name	Time	Method
Frequency of sites with PPD =3 mm, 4 to 5 mm, =6 mm at T0, T1 and (T2);<br>Number of patients treated adjunctively with systemic antibiotics according to recent concept (2004-2018) and according to 2018 guide line.