Natriuretic Brain Pro-peptid Changes in Patients With Chronic Heart Failure Within a Cardiac Rehabilitation Program

Not Applicable

Completed

• Conditions: Chronic Heart Failure

• Registration Number: NCT02087670
• Lead Sponsor: Grupo Rehabilitacion en Salud

Brief Summary

Evaluate pro-BNP levels, oxygen consumption, functional class, and quality of life in patients with chronic heart failure after participating in an exercise program and compare them baseline and 2 months, with another group who underwent an educational program.

Detailed Description

Clinical controlled trial with a double blinded with a aleatory number sequence as the randomization method, patients will be assigned to one of two groups, intervention program (supervises exercise program) and control group (community based exercise)

Study Timeline

• Study Start: 2005-03
• Primary Completion: 2008-01
• Study Completion: 2008-01
• Study First Submitted: 2014-03-12
• Study First Submitted QC: 2014-03-12
• Study First Posted: 2014-03-14
• Results First Submitted: 2014-04-22
• Results First Submitted QC: 2014-07-14
• Results First Posted: 2014-08-07
• Status Verified: 2016-02
• Last Update Submitted: 2016-02-09
• Last Update Posted: 2016-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Patients older than 18 years, diagnosed with heart failure (NYHA) II-IV for more than six months

Exclusion Criteria

• patients with NYHA functional class I, who had attended a cardiac rehabilitation program previously, patients with decompensated diabetes mellitus, hypertension difficult to control, ischemic heart disease in the last month, prior pulmonary embolism, chronic obstructive pulmonary disease, restrictive lung disease , aortic stenosis, new episode of atrial fibrillation and musculoskeletal diseases that limit the performance of physical activity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Natriuretic Brain Pro-peptid	8 weeks

Secondary Outcome Measures

Name	Time	Method
Oxygen Consumption	8 weeks

Trial Locations

Locations (1)

Universidad de Antioquia; 🇨🇴 Medellín, Antioquia, Colombia