The Type of Hepatoglobin in IUGR

• Conditions: Haptoglobin Type

• Registration Number: NCT02127385
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

Intra Uterine Growth Restriction is associated with increased oxidative stress. Haptoglobin (Hp) is an abundant plasma glycoprotein produced in the liver. The function of Hp is as anti oxidant agent, it binds free hemoglobin (Hb) released from red blood cells to decrease oxidative tissue damage. There are 3 differenet genotype of haptoglobin Hp 1-1 Hp 1-2 and Hp 2-2 with different anti oxidant properties and different prevalence ( Hp 1-1, Hp 1-2 and Hp 2-2approximately 16%, 48% and 36% respectively) . we hypotheise that IUGR will be more common and severe in the Hp 2-2 genotype with the less anti oxidant properties.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-03
• Study Start: 2014-04
• Study First Submitted: 2014-04-29
• Study First Submitted QC: 2014-04-29
• Last Update Submitted: 2014-04-29
• Study First Posted: 2014-04-30
• Last Update Posted: 2014-04-30
• Primary Completion: 2015-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

Pregnancies complicated with IUGR -

Exclusion Criteria

NOT INTERESTED DO PARTICIPATE

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
type of haptoglobin	10 weeks	severity of iugr