Intra Uterine Growth Restriction. Minimum Required Evidence-based Care and Neonatal Prognosis: Impact of Healthcare Pathways
试验速览
- 阶段
- 不适用
- 入组人数
- 31,052
- 试验地点
- 1
- 主要终点
- Number of patients diagnosed with Intrauterine growth restriction
研究概览
简要总结
Intrauterine growth restriction (IUGR) is associated with an increase in perinatal mortality and morbidity, as well as longer-term neurological, cognitive, cardiovascular and endocrine complications. In Europe, about 400,000 pregnancies per year are complicated by IUGR. However, antenatal diagnosis seems insufficient in clinical practice, making it impossible to recognize up to 75% of foetuses with IUGR. At a time when the use of good clinical practice has demonstrated a significant improvement in neonatal survival without severe morbidity, foetuses with IUGR are less likely to receive optimal care. Our hypothesis is that the rate of IUGR diagnosed underestimates the rate of actual IUGR.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All birth more than 24 + 0 weeks of amenorrhea at the maternity ward of the hospital Femme-Mère-Enfant
- •from 1st of january 2011 to 31 december 2017.
排除标准
- •Infants born out of the hospital and secondarily hospitalized in the hospital Femme-Mère-Enfant .
- •Multiple pregnancies,
- •children with congenital fetal anomalies
- •pregnancies without first trimester ultrasound (to date the pregnancy)
结局指标
主要结局
Number of patients diagnosed with Intrauterine growth restriction
时间窗: Between 2011 and 2017
IUGR was defined in accordance with the consensus-based definition for early and late IUGR : birthweight \< 3rd centile using French AUDIPOG curves adjusted for term and sex or estimated fetal weight \< 10th centile combined with umbilical artery pulsatility index \> 95th centile or breakage of growth.
次要结局
未报告次要终点