Impaired regulation of Toll-like receptor-2 mediated T helper type 1 responses in NOD2/CARD15 deficient Crohn*s disease patients
- Conditions
- 10017969
- Registration Number
- NL-OMON30051
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Patient with Crohn's disease
at least 18 years of age
known NOD2/CARD15 genotype
Exclusion Criteria
severe anaemia
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Levels of cytokine production, mRNA expression and NFkB activation as a<br /><br>response to stimulation with the different stimuli.</p><br>
- Secondary Outcome Measures
Name Time Method <p>N/A</p><br>