Impaired regulation of Toll-like receptor-2 mediated T helper type responses in patients with inflammatory bowel disease

Recruiting

• Conditions: Crohn's disease; inflammatory bowel disease; 10017969

• Registration Number: NL-OMON33624
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Crohn's disease diagnosed by standard endoscopic, histologic, and radiographic features, inactive disease as assessed by a CDAI<150., and no corticosteroid or immunosuppressive treatment for at least one month before blood withdrawal.

Exclusion Criteria

Patients that not fulfill the inclusion criteria

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences in cytokine production and activated pathways between patients and<br /><br>controls in relation to carriage of the mutation, as determined by ELISA,<br /><br>realtime PCR and microarray analysis.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n/a</p><br>