EUCTR2014-004899-35-NL进行中（未招募）1 期
Morphine for palliative treatment of refractory dyspnea in patients with advanced COPD: benefits and respiratory adverse effects - MORDYC
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •diagnosis of COPD according to the current Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (GOLD) ;
- •optimal pharmacological treatment;
- •Grade 3 or 4 dyspnea on the mMRC;
- •optimal non-pharmacological treatment defined as completed a comprehensive pulmonary rehabilitation program.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 70
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 50
排除标准
- •history of substance misuse;
- •exacerbation of COPD within two weeks of study enrolment;
- •waiting list for lung transplantation;
- •pregnant or childbearing potential not using contraception;?
- •renal failure (creatinine clearance <15mL/min);
- •age under 18;?
- •not being able to read or fill in the questionnaires?or diary;
- •allergy for morphine or its excipients;?
- •concomitant use of irreversible MAO blockers;?
- •use of opioids.
研究者
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