Efficacy of Pilocarpine As a Secretagogue Versus Artificial Tears for the Treatment of Dry Eye
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Ocular Surface Disease Index
研究概览
简要总结
Management approaches for dry eye disease (DED) typically start with low-risk, easily accessible, patient-applied therapies like artificial tears for early-stage disease. As the condition worsens, treatment progresses to more advanced therapies for severe forms of DED. This study aims to compare the effectiveness and safety of pilocarpine as a secretagogue versus artificial tears in the treatment of dry eye disease. Our goal is to provide reliable, high-quality evidence regarding the efficacy of secretagogues, thereby contributing to the development of recommendations that aid clinicians in their decision-making process
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with DED
排除标准
- •Previous Occular surgery.
- •Refuse to particupate.
- •Patients with sjogren syndrome
研究组 & 干预措施
pilocarpine group
干预措施: Pilocarpine (Drug)
artificial tears group
干预措施: artificial tears (Drug)
结局指标
主要结局
Ocular Surface Disease Index
时间窗: At the baseline and after 6 weeks
tear film break-up time
时间窗: At the baseline and after 6 weeks
次要结局
未报告次要终点
研究者
Ehab Tharwat
Prinicipal Investigator
Al-Azhar University