Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty

Not Applicable

Withdrawn

• Conditions: Total Knee Arthroplasty
• Interventions: Procedure: Continuous proximal adductor canal block; Procedure: Continuous femoral nerve block

• Registration Number: NCT02495805
• Lead Sponsor: Yale University

Brief Summary

The purpose of the study is to compare continuous femoral nerve block with continuous proximal adductor canal block for postoperative pain control and rehabilitation.

Detailed Description

Patients meeting the criteria: American Society of Anesthesiologists (ASA) class I and II, that are scheduled for elective total knee arthroplasty, will be recruited into the study. Subjects will be randomized into 2 groups: those who will receive a continuous proximal adductor canal block (ACB) and those who will receive a continuous femoral nerve block (FNB).

Study Timeline

• Study First Submitted: 2015-06-30
• Study First Submitted QC: 2015-07-08
• Study First Posted: 2015-07-13
• Study Start: 2015-09
• Primary Completion: 2016-11
• Study Completion: 2016-11
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-08
• Last Update Posted: 2016-12-09

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients with an American Society of Anesthesiologists Physical Status Classification System (ASA) score of 1 or 2 that are healthy without systemic disease or have mild systemic disease, respectively.
• The patient will need to be able to have decision-making capacity and ability to consent for the study.

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Exclusion Criteria

• Patients with an American Society of Anesthesiologists Physical Status Classification System (ASA) score greater than 2.
• Patients unable to have decision-making capacity and ability to consent for the study.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
adductor canal block (ACB)	Continuous proximal adductor canal block	Subjects randomized to this groups receive a continuous proximal adductor canal block (ACB) during surgery.
femoral nerve block (FNB)	Continuous femoral nerve block	Subjects randomized to this groups receive a continuous femoral nerve block (FNB) during surgery.

Primary Outcome Measures

Name	Time	Method
Motor effects	24 hours (postoperatively)	Subjects' change in motor effects will be assessed as maximum voluntary isometric contraction (MVIC) in the quadriceps muscle.

Secondary Outcome Measures

Name	Time	Method
Pain score	24 hours (postoperatively)	Subjects' pain will be assessed using a numerical pain score, where 10 is the greatest amount of pain.
Opioid consumption	24 hours (postoperatively)	Subjects' pain will be assessed by tracking opioid consumption postoperatively.
Motor effects	On average between 6 and 8 hours postoperatively	Subjects' change in motor effects will be assessed as maximum voluntary isometric contraction (MVIC) in the quadriceps muscle.