Dynamic Interpersonal Therapy (DIT) in SSD patients: trauma, attachment and the brai

Withdrawn

Conditions: Somatic Symptom Disorder
10077546

Registration Number: NL-OMON46100

Lead Sponsor: niversiteit van Tilburg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 120

Inclusion Criteria

Patients with SSD: participants (age 18 -65 years) should suffer from medically unexplained somatic symptoms (MUSS) (e.g. chronic somatic unexplained headaches, chronic fatigue syndrome, unexplained dizziness, whiplash-related complaints, fibromyalgia and irritable bowel syndrome) with no or insufficient medical explanation.

Exclusion Criteria

MUSS symptoms present for less than 6 months, another psychiatric disorder as main classification, age <18 or >65, insufficient mastery of the Dutch language, and unregistered drug or alcohol abuse. Comorbidity and use of psychopharmaceuticals
Patients who agree to participate in the MRI study will be screened for MRI contraindications. Contraindications are metal implants or other metal objects that can not be removed, (possible) pregnancy, and claustrophobia.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>This study predicts a beneficial effect of DIT therapy on several parameters:<br /><br>- Compared to a waiting list group, subjects show an increase in mentalization<br /><br>(about oneself and others), a decrease in levels of stress, pain and fatigue,<br /><br>functional disability.<br /><br>- Associations between childhood trauma and brain structure and function are<br /><br>expected. We expect that structural and functional brain abnormalities realted<br /><br>to trauma play a role in SSD symptoms and that DIT treatment may reverse these<br /><br>abnormalities.<br /><br></p><br>

Secondary Outcome Measures