Proper Dosage of Ketamine in Intravenous Regional Anesthesia
Not Applicable
- Conditions
- Pain.
- Registration Number
- NCT00221871
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
Ketamine added to Lidocaine can increase duration of pain relief following intraveonous regional anesthesia (IVRA). The purpose of this dose response study is to determine the minimum effective dosage of intravenous Ketamine, added to 3 mg/kg of Lidocaine. We anticipate that one dosage will provide us with the proper balance between sufficient anesthesia and minimal side effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age: 18-70
- Weight: 50-100 kg
- ASA: I, II, III
- Carpal tunnel syndrome surgery, tenolysis, ganglion removal or any peripheral hand surgery that can be done by IVRA.
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Exclusion Criteria
- Contraindication to IVRA such as sickle cell disease.
- Any known hypersensitivity reaction to Ketamine.
- History of chronic pain or regular medication with analgesics.
- History of opioid dependence.
- Drug of alcohol abuse.
- Psychiatric disorder.
- Allergy to acetaminophen or codeine
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Health Network
🇨🇦Toronto, Ontario, Canada