The effect of treatment with escitalopram on quality of life and hospitalization rate in depressed patients with systolic heart failure
Phase 3
- Conditions
- heart failure.Heart failure
- Registration Number
- IRCT20230510058142N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
People aged 30 to 75 years
Patients with left ventricular systolic dysfunction (left ventricular ejection fraction <0.40)
Clinical diagnosis of heart failure with at least one episode of dyspnea either with minimal activity or at rest
NYHA classIII or IV
Informed consent of patients
Exclusion Criteria
Previous history of intolerance to SSRI antidepressants
Bipolar or severe personality disorder
Severe suicidal thoughts
Recent dependence on alcohol or drugs
pregnancy
breastfeeding
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: Minnesota Standard Questionnaire.
- Secondary Outcome Measures
Name Time Method Hospitalization rate. Timepoint: The beginning of the study and 2 month later. Method of measurement: Patient files and Questionnaire.