A clinical trial to study the effect of Escitalopram with and without Mindfulness-based therapy in patients who develop depression and anxiety after suffering from a heart attack
- Conditions
- Health Condition 1: I219- Acute myocardial infarction, unspecified
- Registration Number
- CTRI/2024/03/063401
- Lead Sponsor
- eha Mittal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Those with written informed consent.
2. Age group between 18 to 65 years of age.
3. All genders.
4.Ability to attend all required study visits.
5.Patients with recent diagnosis of Myocardial Infarction.
6.Admitted to Cardiology Unit of KIMS, Bhubaneswar.
7.Patients who are medically stable and planned for discharge
1.Patients with diagnosis of Depression or Anxiety before the myocardial infarction
2.Patients with a major mental illness, like schizophrenia or bipolar disorder.
3.Patients currently on any psychotropic drugs.
4.Patients with Prominent Cognitive Impairment with a score less than 24 on screening Folstein Mental Status Exam.
5.Patients with a Comorbid Medical illness that is likely to interfere in assessment.
6.Persons with cancers and other debilitating diseases, or with life expectancy less than one year
7.Patients with Active Dependence (Except Tobacco).
8.Uncontrolled hypertension, or carotid artery stenosis; and acute medical or psychiatric symptoms likely to interfere with study participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Treatment response will be defined as 50 % reduction in HAM-D scores for patients with Depression <br/ ><br>2.Treatment response will be defined as 50 % reduction in HAM-A scores for patients with Anxiety <br/ ><br>Timepoint: Time of discharge, 4 weeks after discharge and 8 weeks after discharge
- Secondary Outcome Measures
Name Time Method Incidence of depressive or anxiety symptoms as measured by Hospital Anxiety and Depression Scale in 4 and 8 weeks follow upTimepoint: Time of discharge, 4 weeks after discharge and 8 weeks after discharge