A single-blind, randomized controlled trial comparing efficacy between low-fluence alexandrite 755-nm picosecond laser and low-fluence neodymium-doped yttrium aluminum garnet (Nd:YAG) 1064-nm picosecond for the treatment of UVB-induced hyperpigmentatio
Phase 3
Completed
- Conditions
- reduction of UVB-induced hyperpigmentationlaserhyperpigmentation
- Registration Number
- TCTR20201104004
- Lead Sponsor
- Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
aged of 18-65 years with Fitzpatrick skin type II-IV
Exclusion Criteria
had other skin diseases including active skin infection, inflammatory lesions, wound, and skin cancer
currently used chemical peel, whitening agents or received laser therapy 1 month before enrollment
immunocompromised patients
photosensitivity or currently on photosensitizing medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mean relative lightness index evaluate at every visit colorimeter (DSM II ColorMeter®)
- Secondary Outcome Measures
Name Time Method patient satisfaction scores evaluate at every visit visual analogue scale on satisfaction of treatment,physician improvement scores evaluate at every visit visual analogue scale on improvement of hyperpigmentation