Vascular changes in retina in amblyopic eyes verse in healthy eyes
Not Applicable
- Conditions
- Health Condition 1: H53-H54- Visual disturbances and blindnessHealth Condition 2: H53-H54- Visual disturbances and blindness
- Registration Number
- CTRI/2021/11/038090
- Lead Sponsor
- Varsha Negi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients in the age group of 6 to18 years with strabismic and anisometropic amblyopia (difference of at least 2 lines in BCVA between 2 eyes)
2.Age and Gender matched patients referred to OPD for routine eye examination will be recruited as control eyes.
Exclusion Criteria
1.Poor quality scans and un co-operative child.
2.Children with spherical refractive errors of +/- 5.00 diopters(D) or greater and cylindrical refractive errors of 3.00 diopters(D) or greater.
3.Children with poor fixation, nystagmus, eccentric fixation.
4.Ocular diseases viz. cataract, corneal opacities, uveitis, retinal pathology
5.History of intraocular surgery
6.History of any systemic condition that could alter the retinal microvasculature
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Foveal Avascular Zone Measurements (mm square) <br/ ><br>2.Macular Vessel density percentage of SCP scan <br/ ><br>3.Macular Vessel density percentage of DCP scan <br/ ><br>Timepoint: Baseline <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.Central Macular thickness (�µm) <br/ ><br>2.Peripapillary Retinal nerve fiber layer thickness (�µm) <br/ ><br>Timepoint: 1 year