Evaluation the effect of pregabalin on succinylcholine fasciculation and myalgia
Phase 2
- Conditions
- fasciculation.Fasciculation
- Registration Number
- IRCT20160430027677N11
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
aged 20 to 60 years old
American Society of Anesthesiologists class I and II
Exclusion Criteria
Patients with BMI above 25 kg/m²
history of central nervous system disease
renal dysfunction
history of allergy to any of the drugs used during the study
history of peptic ulcer disease and antacid therapy
patients who used analgesic drug within 24 hours before surgery
used any kind of sedative drug
patients with a history of taking antidepressants and calcium channel blockers
patients who had contraindication for succinylcholine
patients whose laparoscopic cholecystectomy will be replaced with open cholecystectomy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasciculation. Timepoint: Immediately after injection of succinylcholine. Method of measurement: visual analog scale.
- Secondary Outcome Measures
Name Time Method Incidence of myalgia. Timepoint: 6, 12, 18, and 24 hours after surgery. Method of measurement: visual analog scale.;Severity of myalgia. Timepoint: 6, 12, 18, and 24 hours after surgery. Method of measurement: visual analog scale.