A study to assess the Arterial blood to expired carbon dioxide difference to predict mortality and morbidity in patients with sepsis.
Not Applicable
- Conditions
- Health Condition 1: A419- Sepsis, unspecified organism
- Registration Number
- CTRI/2024/03/063677
- Lead Sponsor
- Dr Radhika K T
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Aged above 18 years
2.Clinically suspected or proven sepsis with or without septic shock requiring invasive ventilator support.
Exclusion Criteria
1. Chronic obstructive pulmonary disease
2. Interstitial lung disease
3. Bronchial asthma
4. Obstructive sleep apnoea
5. Cardiogenic shock
6. More than 7 days since the suspicion of sepsis
7. Post cardiac arrest resuscitated patients
8. Pregnancy
9. Pulmonary embolism
10. Patients requiring all non invasive methods of ventilatory support
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial to end tidal carbon dioxide difference as a marker of in-hospital mortality in patients with suspected or proven sepsis.Timepoint: 28 days from the day of admission.
- Secondary Outcome Measures
Name Time Method Arterial to end tidal carbon dioxide difference as a marker of morbidity in patients with suspected sepsis in terms of <br/ ><br>-No of days of hospital stay <br/ ><br>-No of days of ICU stay <br/ ><br>-No of days of ventilatory support <br/ ><br>-Need for vasoactive support; average dose per day and duration <br/ ><br>-Requirement of renal replacement therapyTimepoint: 28 days from the day of admission;Correlation between Arterial to end tidal carbon dioxide difference and SOFA Score as well as Capillary refill time.Timepoint: 28 days from the day of admission