Comparative evaluation of pain relieving effects of 2 doses of Dexamethasone given along with Bupivacaine during surgery

Phase 4

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/06/043190
• Lead Sponsor: School of medical sciences and research

Brief Summary

Comparison of analgesic effect of different doses of Dexamethasone as an adjuvant to Bupivacaine in ultrasound guided supraclavicular brachial plexus block. Aim: To compare the analgesic effect of Dexamethasone 8mg Vs 4mg as an adjuvant to Bupivacaine in ultrasound guided Supraclavicular brachial plexus block. Study design: Prospective, observational, randomised comparative double blinded study. Materials and Methods: thirty six patients will be divided into three groups, 12 patients each. Group D8 will receive bupivacaine 0.5% 20 mL + dexamethasone 8mg 2 mL, group D4 will receive Bupivacaine 0.5% 20 ml + dexamethasone 4mg 1ml+ 1ml NS and group B will receive 20 ml Bupivacaine + 2ml NS. We will compare the onset of sensory and motor blocks, duration of analgesia and incidence of complications.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-13
• Last Update Posted: 2022-11-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

ASA 1 & 2 Ortho upper limb surgeries.

Exclusion Criteria

• Patient refusal to participate in study.
• History of allergy to local anesthetic and Dexamethasone.
• History of usage of corticosteroids, opioids and any other analgesics.
• Infection at the site of injection.
• Pregnant females.
• Significant cognitive or psychiatric history.
• History of endocrine disease- Diabetes mellitus and thyroid disease History of CNS, cardiovascular and renal disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate and compare the duration of analgesic effect with two different doses Dexamethasone (8mg Vs 4 mg) as an adjuvant to Bupivacaine in supraclavicular brachial plexus block.	assessment of pain will be done till 20 mins just after giving the block and then in postoperatively at 6 hrs,9 hrs, 12hrs and 24hrs.

Secondary Outcome Measures

Name	Time	Method
To evaluate and compare the time required with respect to achieve:	complete onset of sensory block

Trial Locations

Locations (1)

OT Complex, Sharda Hospital; 🇮🇳 Nagar, UTTAR PRADESH, India

OT Complex, Sharda Hospital

🇮🇳Nagar, UTTAR PRADESH, India

Anshil Bhatia

Principal investigator

9896618924

Anshil.bhatia@sharda.ac.in