Effect of Dexmedetomidine and Remimazolam on Body Temperature in Patients Undergoing Spinal Anesthesia
Not Applicable
Completed
- Conditions
- Temperature Change, Body
- Registration Number
- NCT06853067
- Lead Sponsor
- SMG-SNU Boramae Medical Center
- Brief Summary
This study aims to evaluate the effect of dexmedetomidine and remimazolam on body temperature in patients undergoing spinal anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 122
Inclusion Criteria
- Patients scheduled for elective surgery under spinal anesthesia
Exclusion Criteria
- Severe vascular disease
- Thyroid dysfunction
- Coagulopathy
- Neuromuscular disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Incidence of hypothermia during surgery Body temperature is monitored during surgery Incidence of temperature \<36℃ during spinal anesthesia is assessed.
- Secondary Outcome Measures
Name Time Method Incidence of hypothermia in the post-anesthesia recovery room Immediately after entering the the post-anesthesia recovery room, until the discharge Body temperature is assessed in the in the post-anesthesia recovery room
Incidence of shivering during surgery and in the post-anesthesia recovery room During surgery and in the post-anesthesia recovery room Occurrence of shivering is assessed.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie dexmedetomidine and remimazolam's modulation of body temperature during spinal anesthesia?
How does the combination of dexmedetomidine and remimazolam compare to standard sedatives like propofol in preventing hypothermia during spinal procedures?
Which biomarkers correlate with hypothermia risk in patients administered alpha-2 adrenergic and GABA-A agonists during spinal anesthesia?
What are the incidence rates of bradycardia or respiratory depression with dexmedetomidine-remimazolam in spinal anesthesia trials?
Are there alternative sedative-anesthetic combinations targeting alpha-2 adrenergic and GABA-A receptors for hypothermia prevention in spinal surgery?
Trial Locations
- Locations (1)
SMG-SNU Boramae Medical Center
🇰🇷Seoul, Select State/Province, South Korea
SMG-SNU Boramae Medical Center🇰🇷Seoul, Select State/Province, South Korea