Embryo development of fresh versus vitrified metaphase II after intracytoplasmic sperm injection (ICSI): a sibling-oocyte study

Completed

• Conditions: Intracytoplasmic sperm injection cases, oocyte vitrification; Pregnancy and Childbirth; Fertilisation difficulties

• Registration Number: ISRCTN60158641
• Lead Sponsor: G.EN.E.R.A. - Clinica Valle Giulia (Italy)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05-29
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Between September 2008 and February 2009 consecutive patients not older than 42 years of age, presenting greater than 6 normal appearing metaphase II (MII) oocytes and undergoing ICSI treatment with ejaculated sperm in the Centre for Reproductive Medicine GENERA in Rome.

Exclusion Criteria

1. Female partner older than 42 years old
2. Less than 6 normal appearing MII oocytes retrieved
3. Surgically extracted spermatozoa
4. Very severe oligoastenoteratozoospermia (motile sperm count less than 500,000/ml after preparation)
5. Patients enrolled in our polar body biopsy programme

Study & Design

• Study Type: Interventional
• Study Design: Not specified