Effects of Dexmedetomidine on intraoperative vital parameters and drug requirements when used with general anaesthesia in obese patients undergoing laparoscopic bariatric surgery.
Not Applicable
Completed
- Conditions
- Health Condition 1: E669- Obesity, unspecified
- Registration Number
- CTRI/2019/03/018208
- Lead Sponsor
- Dr Divyangna Sapra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 72
Inclusion Criteria
1) American Society of Anaesthesiologists (ASA) Grade II, III
2) Basal Metabolic Index (BMI) >30
3) Patients scheduled for laparoscopic bariatric surgery under general anaesthesia
Exclusion Criteria
Patients with
1) Heart Block or severe ventricular dysfunction,
2) Allergy to Alpha 2 adrenergic drugs,
3) hepatic impairment,
4) Hypotension,
5) Bradycardia,
6) pregnancy or breast feeding.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraoperative propofol requirementTimepoint: This will be assessed at following time points: <br/ ><br>1. At time of induction, <br/ ><br>2. During the period of maintenance, <br/ ><br>3. During total duration of surgery
- Secondary Outcome Measures
Name Time Method Intraoperative antihypertensive (Nitroglycerine and Labetalol) requirementTimepoint: During total duration of surgery;Intraoperative haemodynamics (Blood pressure- Systolic, Diastolic and Mean, heart rate, peripheral oxygen saturation)Timepoint: These will be assessed at following 9 time points: <br/ ><br>1. Prior to induction, <br/ ><br>2. After endotracheal intubation, <br/ ><br>3. At the time of Gastric calliberation tube (GCT) insertion, <br/ ><br>4. At the time of incision, <br/ ><br>5. At the time of start of carbo-peritoneum, <br/ ><br>6. At the time of reverse Trendelenburg positioning, <br/ ><br>7. At the time of carbo-peritoneum release, <br/ ><br>8. At the time of repositioning, <br/ ><br>9. Immediately after extubation.