The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease

Not Applicable

Completed

• Conditions: Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease
• Interventions: Behavioral: Weight-shifting training

• Registration Number: NCT04288024
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

(1) postural and suprapostural performance of a dual task would be differently affected by the strategy of task prioritization and (2) the cortical activation is different according to attentional focus strategies.

Detailed Description

These hypothesis would be tested by gait performance, suprapostural accuracy and relative power spectrum of EEG.

Study Timeline

• Status Verified: 2020-02
• Study First Submitted: 2020-02-24
• Study Start: 2020-02-25
• Study First Submitted QC: 2020-02-26
• Study First Posted: 2020-02-27
• Primary Completion: 2020-06-22
• Study Completion: 2020-06-22
• Last Update Submitted: 2021-03-16
• Last Update Posted: 2021-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• 1. modified H-Y stage II-III Parkinson's disease 2. No other diseases 3. Non-demented PD 4. Non-tremor PD

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Exclusion Criteria

• None

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Suprapostural	Weight-shifting training	During training, participants in this group are instructed to focus on their suprapostural task during weight-shifting.
Postural	Weight-shifting training	During training, participants in this group are instructed to focus on their posture during weight-shifting.

Primary Outcome Measures

Name	Time	Method
EEG relative power in the theta band	60 minutes	postural and suprapostural performance of a dual task
EEG relative power in the delta band	60 minutes	postural and suprapostural performance of a dual task
COP trajectory recorded from the force plate	60 minutes	performance of the postural task
Angles from inclinometer	60 minutes	performance of the suprapostural task
EEG relative power in the alpha band	60 minutes	postural and suprapostural performance of a dual task
EEG relative power in the gamma band	60 minutes	postural and suprapostural performance of a dual task
EEG relative power in the beta band	60 minutes	postural and suprapostural performance of a dual task

Secondary Outcome Measures

Name	Time	Method
Gait velocity from GAITRite	5 minutes	gait performance
Cadence from GAITRite	5 minutes	gait performance
Mean step length from GAITRite	5 minutes	gait performance
Step-to-step variability from GAITRite	5 minutes	gait performance

Trial Locations

Locations (1)

National Taiwan University; 🇨🇳 Taipei, Taiwan