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Clinical Trials/NCT01748474
NCT01748474CompletedPhase 2

Effect of Short-term Oxygen Therapy on Cardiopulmonary Exercise Capacity in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension

University of Zurich2 sites in 1 country20 target enrollmentStarted: December 2012Last updated:
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Conditions

Trial Snapshot

Phase
Phase 2
Status
Completed
Enrollment
20
Locations
2
Primary Endpoint
Watt
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

In a randomized, sham-controlled trial the investigators will test whether supplemental oxygen given during cardiopulmonary exercise testing will improve exercise performance and physiological parameters in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Supportive Care
Masking
Triple (Participant, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
20 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Watt

Time Frame: 1 day

exercise time

Time Frame: 1 day

Secondary Outcomes

  • Peak oxygen uptake(1 day)
  • Respiratory exchange ratio(1 day)
  • ventilatory equivalent of carbon dioxide (VE/VCO2) slope(1 day)
  • end-tidal pressures of carbon dioxide (PET CO2)(1 day)
  • Changes in arterial blood parameters(1 day)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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