OCT Technology Development to Assess Ocular Integrity and Characterize Ocular Integrity and Intraocular Scatterers

Duke University1 site in 1 country14 target enrollmentNovember 14, 2018

ConditionsUveitis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Uveitis
Sponsor: Duke University
Enrollment: 14
Locations: 1
Primary Endpoint: Concordance
Status: Completed
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to develop and demonstrate new technologies that will enable a non-contact, compact eye imaging system based on OCT to assist an early responder in acute care settings (like an emergency room) to help assess eye trauma and inflammation (swelling inside the eye).

Registry

clinicaltrials.gov

Start Date

November 14, 2018

End Date

March 10, 2021

Last Updated

3 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Duke University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Pre-clinical: employees or students (over the age of 18) of the Duke Eye Center or Biomedical Engineering willing to be imaged with OCT system
•Pilot (ER): patients (over the age of 18) presenting emergently to the Duke Emergency room with traumatic eye injuries and/or suspected open globe
•Pilot (Uveitis): patients presenting to the Duke Eye Center with active uveitis and microhyphema or hyphema; patients who have independently consented to undergo vitreous tap or biopsy for their uveitis care at the Duke Eye Center

Exclusion Criteria

•Pre-clinical: subject cannot be a direct report to any of the PIs or other key personnel of this study
•Pilot (ER): hemodynamically unstable, unable to consent
•Pilot (Uveitis): unable to consent; cornea or lens opacity/scar which would block the imaging modality