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Clinical Trials/NCT05755347
NCT05755347
Completed
Not Applicable

Assessing Functional Status Needs Via Patient-Reported Outcomes Measures in the Pre-treatment Setting With Metastatic Breast Cancer Patients

UNC Lineberger Comprehensive Cancer Center1 site in 1 country50 target enrollmentMarch 17, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
UNC Lineberger Comprehensive Cancer Center
Enrollment
50
Locations
1
Primary Endpoint
Physical activity levels
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this single-site non-randomized study is to identify areas of need related to functional status and overall health, including nutrition and mental health in subjects with metastatic breast cancer (MBC). A decline in functional status is observed after breast cancer diagnosis and exacerbated by treatment. Declining functional status impacts the quality of life and can lead to increased comorbidity burden, hospitalization, and increased mortality. Functional status is assessed by specific provider-graded scales. Patient Reported Outcome (PRO) measures may better assess certain aspects of patient health and symptom domains. Thus, potentially supporting the future implementation of effective prehabilitation strategies. This study explores whether a PRO-based survey will identify the physical and emotional health and the social and financial status of patients newly diagnosed with MBC.

Registry
clinicaltrials.gov
Start Date
March 17, 2023
End Date
February 5, 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Written informed consent was obtained from participants in the study and HIPAA authorization for release of personal health information.
  • Subject is willing and able to comply with study procedures based on the judgment of the investigator or protocol designee.
  • Age ≥ 18 years at the time of consent.
  • Recent diagnosis of new metastatic breast cancer at time of screening.

Exclusion Criteria

  • Exclusion Criteria
  • Inability to read or speak English.
  • Dementia, altered mental status, or any psychiatric condition as determined by clinical or study team that would prohibit the understanding or rendering of informed consent.
  • Current incarceration.
  • Subject has already received treatment for metastatic breast cancer prior to screening.

Outcomes

Primary Outcomes

Physical activity levels

Time Frame: Baseline

Physical activity levels will be measured using the Godin Leisure-Time Exercise Questionnaire. Godin Leisure-Time Exercise Questionnaire has 3 dichotomous questions, answers will be "yes" or "no". There will be reason questions if the answer is no.

Secondary Outcomes

  • Diet quality(Baseline)
  • Health-related quality of life - FACT-G(Baseline)
  • health-related opinions(Baseline)
  • the percentage of subjects referred(Baseline)
  • Barriers to access exercise(Baseline)
  • Acceptability of survey(Baseline)
  • Health-related quality of life - PROMIS(Baseline)

Study Sites (1)

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