A Study to Observe the Change of the Biological Signal (Heart Rate) During the Combined Pituitary Stimulation Test
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pituitary Adenoma
- Sponsor
- Seoul St. Mary's Hospital
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Changes in Heart rate variability according to the types of pituitary adenoma
- Last Updated
- 8 years ago
Overview
Brief Summary
Several studies have been reported that heart rate is known to be associated with prognosis in chronic diseases and acute diseases. For example, a decrease in heart rate following myocardial infarction may lead to a higher mortality rate. It is also known to predict heart failure, diabetic neuropathy, and even depression.
The combined pituitary function test artificially induces hypoglycemia to observe the secretion of pituitary hormone. The degree of change in heart rate during hypoglycemia can predict the adequacy of the test, and heart rate can be changed according to the characteristic of the tumor. Also, the prognosis can be predicted based on this.
In our study, we used a licensed device approved by KFDA (Korea Food and Drug Administration) to measure heart rate variability in patients with pituitary adenoma.
Investigators
Dong Jun Lim
Professor
Seoul St. Mary's Hospital
Eligibility Criteria
Inclusion Criteria
- •Over 19 year old
- •Those with Normal blood pressure range:
- •90mmHg \<systolic \<140mmHg, 60mmHg \<diastolic \<100mmHg
- •Voluntary participants who visited Seoul St. Mary's Hospital
Exclusion Criteria
- •Those who have been diagnosed with sleep disorders, diabetes, arrhythmia, psychiatric disorder, physical or mental breakdown, drug addicts
- •Diabetes, hypertension, cardiovascular disease diagnosed by taking a drug related to the disease
- •Pregnant or lactating women
- •Those who drank within 12 hours before participating in the trial
- •Those who are deemed inappropriate by clinical trial researchers
Outcomes
Primary Outcomes
Changes in Heart rate variability according to the types of pituitary adenoma
Time Frame: 5 month of initial recruit