Enhancing Renal Graft Function During Donor Anesthesia

Not Applicable

Recruiting

• Conditions: Transplant;Failure,Kidney; Anesthesia; Renal Failure Chronic

• Registration Number: NCT03778944
• Lead Sponsor: Nazmy Edward Seif

Brief Summary

Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess \& compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-12-14
• Study First Submitted QC: 2018-12-17
• Study First Posted: 2018-12-19
• Study Start: 2018-12-20
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-11
• Last Update Posted: 2025-02-12
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• end-stage renal disease, for living-donor kidney transplantation

Exclusion Criteria

• severe cardiac or hepatic dysfunction
• coagulopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Post-operative creatinine clearance	7 days	Post-operative creatinine clearance level of the transplanted kidney graft is measured in ml/min

Trial Locations

Locations (1)

Kasr Al-Ainy Hospital, Cairo University; 🇪🇬 Cairo, Egypt