Continuous Spinal Anesthesia in Renal Transplantation

Not Applicable

Active, not recruiting

• Conditions: Anesthesia; Transplant;Failure,Kidney; Renal Failure Chronic
• Interventions: Procedure: Continuous spinal anesthesia; Procedure: General anesthesia

• Registration Number: NCT03436368
• Lead Sponsor: Nazmy Edward Seif

Brief Summary

Renal transplantation is now recognized as a treatment of choice for patients with end-stage renal disease. An adequate anesthetic technique should achieve hemodynamic stability and enhance perfusion of the transplanted kidney. The aim of this study is to assess the use \& effects of continuous spinal anesthesia for kidney transplantation recipients, compared with balanced general anesthesia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-02-12
• Study First Submitted QC: 2018-02-12
• Study First Posted: 2018-02-19
• Study Start: 2018-02-20
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-11
• Last Update Posted: 2025-02-12
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA class III or IV
• End-stage renal disease
• Renal transplantation candidate patients

Exclusion Criteria

• Any condition contra-indicating regional anesthesia
• Coagulopathy
• Allergic to any of the drugs used during the procedure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CSA group	Continuous spinal anesthesia	Continuous Spinal Anesthesia
GA group	General anesthesia	General Anesthesia

Primary Outcome Measures

Name	Time	Method
Mean ABP	12 hours	Change in Mean Arterial Blood Pressure measured in mmHg.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction score	24 hours	Patient satisfaction Score defines the degree of patient satisfaction with the anesthetic experience and is assessed after recovery. It is graded as excellent "E" (best score), fair "F" or poor "P" (worst score).
Visual Analogue Score for pain "VAS"	12 hours	Visual Analogue Score for pain measures the degree of pain experienced by the patient during the procedure. VAS is graded from 0-10 \[where 0=no pain, 10= worst pain\].

Trial Locations

Locations (1)

Kasr Al-Ainy Hospital, Cairo University; 🇪🇬 Cairo, Egypt