MANAGEMENT OF ISOLATED GINGIVAL RECESSIONS USING HYALURONIC ACID GEL WITH OR WITHOUT PLATLET RICH FIBRIN(PRF)MEMBRANE IN PINHOLE SURGICAL TECHNIQUE- A RANDOMIZED CLINICAL TRAIL
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
研究概览
简要总结
Gingival recession is a common periodontal condition that necessitates effective therapeutic interventions .Conventional methods in use have associated donor site complications that has led to the pinhole surgical technique (PST), which holds promise as a minimally invasive, predictable method for obtaining optimal patient-based outcomes. PST when paired with regenerative materials like platelet rich fibrin (PRF),enamel matrix derivatives, hyaluronic acid, etc it inherently promotes tissue regeneration.
Hyaluronic acid (HA)is a potent anti-inflammatory agent and modulates wound healing due to its ability to scavenge the inflammatory cells. Platelet rich fibrin(PRF) derived from the patient’s own blood, is a safe, and cost-effective biomaterial that enhances treatment outcomes by releasing growth factors that support wound healing, angiogenesis, and tissue regeneration, making it a proven adjunct in the treatment of gingival recession.
Due to limited evidence regarding the use of HA gel with PRF membrane in PST for isolated gingival recessions, this study aims to compare the efficacy of HA gel, with or without PRF membranes using pinhole surgical technique in treating Miller’s Class I and II gingival recessions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who consent to participate in the study.
- •Presence of at least 20 teeth.
- •Miller Class I and II gingival recession with greater than or equal to 2mm depth.
- •Presence of identifiable CEJ and adequate width of keratinized tissue apical to recession.
- •Adequate plaque control.
- •No clinical signs of active periodontal disease or inflammation at the treatment site.
排除标准
- •1 Patients with relevant systemic condition or disease and, on drug therapy.
- •2 Patients with presence of occlusal interferences such as malposition or rotated teeth.
- •3 Habitual smokers and tobacco chewers.
- •4 Patients with a history of previous mucogingival or periodontal surgery at the experimental site in last 6 months.
- •5 Presence of gingival recession with caries, restoration or with pulpal pathology.
研究者
Keerthi V
The oxford Dental College