Endotracheal Suctioning: open or closed?

Completed

• Conditions: Mechanical ventilation, complications; Ventilation; Respiratory

• Registration Number: ISRCTN75875670
• Lead Sponsor: niversity Medical Center Utrecht (UMCU) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-12-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

All adult ICU patients receiving mechanical vetilators (MV) will be included and, during six months, be subjected to the same endotracheal suctioning (ES)-procedure.

Exclusion Criteria

No exclusion criteria. Preference of ES system is often based on assuptions, there is currently no scientific evidence available to prefer one system over the other.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of cross-transmission (primary endpoint), defined as acquired colonisation with a genetically identical pathogen with an epidemiological linkage to a potential source patient.

Secondary Outcome Measures

Name	Time	Method
1. Length of stay in ICU<br>2. Antibiotic use<br>3. Cardio-respiratory adverse events (hypoxaemia, cardiac arrhythmia, damage to respiratory mucosa)<br>4. Mortality<br>5. The incidence of ventilator-associated pneumonia (VAP) and cost-efficacy