Endotracheal suctioning: open or closed?
- Conditions
- In mechanically ventilated patients, endotracheal suctioning will be performed when indicated. During two 6-month periods all ES procedures will be performed with either OSS or CSS. After 6 months, 1 month of wash out/wash in is planned, during which the system is changed.
- Registration Number
- NL-OMON22462
- Lead Sponsor
- one
- Brief Summary
Jongerden IP, Rovers MM, Grypdonck MH, Bonten MJ. Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta analysis. Crit Care Med, accepted.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
All adult ICU patients receiving MV will be included and, during 6 months, be subjected to the same ES-procedure.
Exclusion Criteria
No exclusion criteria. Preference of ES system is often based on assuptions, there is currently no scientific evidence available to prefer one system over the other.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of cross-transmission (primary endpoint), defined as acquired colonization with a genetically identical pathogen with an epidemiological linkage to a potential source patient.
- Secondary Outcome Measures
Name Time Method ength of stay in ICU, antibiotic use, cardio-respiratory adverse events (hypoxemia, cardiac arrhythmia, damage to respiratory mucosa), mortality, the incidence of VAP and cost-efficacy.