NL-OMON50795撤回不适用
Short-course aminoglycosides as adjunctive treatment in adults with sepsis - SAGA
niversitair Medisch Centrum Utrecht0 个研究点目标入组 3,140 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 3,140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1) Age ><= 18 years
- •2) Presenting to the ER
- •3) Suspicion of bacterial infection of unknown origin, primary suspected
- •urinary origin or primary suspected abdominal origin.
- •4) National Early Warning Score (NEWS) or Modified Early Warning Score (MEWS) *
- •5) Requiring intravenous antibiotic treatment and hospitalization.
排除标准
- •1) Working diagnosis at the ER of pneumonia.
- •2) Chemotherapy induced neutropenia as this is considered a separate entity in
- •the guidelines.
- •3) Pre-existing renal failure defined as a GFR < 30, due to a relative
- •contra-indication for aminoglycosides.
- •4) Allergy for cephalosporins or aminoglycosides, known prior to the start of
- •5) Indication for empirical coverage of ESBL-producing gram-negative bacteria
- •according to the Dutch sepsis guidelines, i.e. known colonization or infection
- •with ESBL-producing gram-negative bacteria in the prior year.
研究者
相似试验
尚未招募
不适用
Short-course aminoglycosides as adjunctive treatment in adults with sepsisSepsisNL-OMON29602niversity Medical Center Utrecht3,140
招募中
不适用
Short-course aminoglycosides as adjunctive treatment in adults with sepsisinfection10004018sepsisNL-OMON53650niversitair Medisch Centrum Utrecht3,140
进行中（未招募）
1 期
Aminoglycosides for sepsisPatients admitted with sepsis of unknown origin, suspected urinary origin or suspected abdominal originEUCTR2021-001840-83-NLniversity Medical Center Utrecht3,140
进行中（未招募）
1 期
Combination lock01 - Impact of aminoglycosides-based antibiotics combination and protective isolation on outcomes in critically-ill neutropenic patients with sepsis:A randomized 2 by 2 factorial design randomized pragmatic trialAdult patients admitted to intensive careCTIS2024-514042-36-00Assistance Publique Hopitaux De Paris340
招募中
3 期
Combination lock01 - Impact of aminoglycosides-based antibiotics combination and protective isolation on outcomes in critically-ill neutropenic patients with sepsis:A randomized 2 by 2 factorial design randomized pragmatic trial2024-514042-36-00Assistance Publique Hopitaux De Paris340