Feasibility study of lidocaine for peripheral venous pain induced by oxaliplatin.
Phase 1
- Conditions
- colorectal cancer
- Registration Number
- JPRN-UMIN000011393
- Lead Sponsor
- Saito Yukokai Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Not provided
Exclusion Criteria
1. History of treatment with oxaliplatin 2. Pain or cutaneous symptoms in the arm 3. Unable to be self-assessment of pain 4. Contraindication for the each medicine 5. Serious abnormalty in ECG requiring treatment 6. Administration of anti-arrhythmic. 7. Administration of adjuvant analgesics in neuropathic pain 8. Sever complications 9. Pregnancy, or lactation 10. History of drug hypersenstitivity. 11. Others
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate feasibility and to determine the recommended dose
- Secondary Outcome Measures
Name Time Method The degree of venous pain Blood concentration of lidocaine : pharmacokinetics