Estriol use at the entrance and inside of vagina improving coital pain in women after menopause

Phase 2

• Conditions: Dyspareunia; N94.1

• Registration Number: RBR-3y8v57
• Lead Sponsor: Faculdade de Medicina de Ribeirão Preto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women with a clinical diagnosis of menopause; FSH over 40 mIU/ml with a minimum age of 40 years old and and maximum age of 65 with sex including penetration of penis into vagina and complaining of pain during penetration, which appeared in peri or postmenopausal with active sexual partners and stable relationship.

Exclusion Criteria

Women will be excluded if previous use of steroids in genital area in the last month; thromboembolism history; renal insufficiency; cholestatic jaundice; degenerative vulvar pathology; breast, endometrial, vulvar and vaginal cancer history; prior radiotherapy to the genital region; smoking; acute urogenital infections (vulvovaginitis, urinary tract infection and genital herpes); genital prolapse grades II, III and IV by Baden Walker; systemic hormonal therapy in the last three months; in treatment of depression; suffering from diabetes, thyroid disorders or cognitive restrictions.

Study & Design

• Study Type: Intervention
• Study Design: Not specified