MedPath

Effect of vaginal estriol 0.03 mg with Lactobacillus acidophilus on incidence of bacterial vaginosis in patient using pessary for treatment of pelvic organ prolapse

Not Applicable
Conditions
Postmenopausal women who diagnosed as pelvic organ prolapse and chosing vaginal pessary for treatment option
pelvic organ prolapse&#44
pessary&#44
vaginal estrogen&#44
gynoflor
Registration Number
TCTR20180329001
Lead Sponsor
Ratchadapiseksompotch Fund
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
Female
Target Recruitment
80
Inclusion Criteria

Postmenopausal women
Symptomatic pelvic organ prolapse
Choose vaginal pessary as choice of treatment
Not using exogenous estrogen

Exclusion Criteria

Hypersensitivity to the anti-infective agent or test preparation
Vaginal bleeding of unknown origin
Estrogen-dependent neoplastic disease
Breast cancer
Immunosuppression and clinically manifest sexually transmitted diseases
History of bacterial vaginosis, trichomoniasis or vulvovaginal candidiasis before enrollment

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The incidence of bacterial vaginosis 3 months Amsel’s criteria
Secondary Outcome Measures
NameTimeMethod
The pessary-related complications 3 months Normal flora index and Questionnaire (ICIQ-VS) and Visual analog scale
© Copyright 2025. All Rights Reserved by MedPath