Alendronate in the Prevention of Collapse of Femoral Head in Non-Traumatic Osteonecrosis

Phase 4

• Conditions: Non-Traumatic Osteonecrosis

• Registration Number: NCT00265252
• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital

Brief Summary

To determine the cumulative incidence of total hip replacement, time to event after treatment with Fosamax or placebo during the study peroid

Detailed Description

To determine the cumulative incidence of total hip replacement and collpase of femoral head, time to event after treatment with Fosamax or placebo during the study peroid

Study Timeline

• Study Start: 2005-06
• Study First Submitted: 2005-12-12
• Study First Submitted QC: 2005-12-12
• Study First Posted: 2005-12-14
• Status Verified: 2007-04
• Last Update Submitted: 2008-02-26
• Last Update Posted: 2008-02-27
• Study Completion: 2008-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• osteonecrosis of femoral head
• be able to provide singed informed consent

Read More

Exclusion Criteria

• prior bisphosphonate use
• pregnant or lactating woman
• bilateral hip replacement

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the cumulative of total hip replacement

Secondary Outcome Measures

Name	Time	Method
necrotic area
Harris hip score

Trial Locations

Locations (1)

Kaohsiung Medical University Chung-Ho Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan