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Calculation of Ejection Fraction from Left Heart Valve Displacement

Not Applicable
Completed
Conditions
Health Condition 1: -
Registration Number
CTRI/2022/11/046989
Lead Sponsor
ady Hardinge Medical College
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
150
Inclusion Criteria

1. Patients admitted to the intensive care unit

2. Patients more than 18 years and less than 60 years in age

3. Patients of either sex

Exclusion Criteria

1. Patients with cardiac valvular diseases

2. Patients with poor cardiac window

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Spearman correlation between MAPSE and ejection fraction by modified Simpson’s <br/ ><br>methodTimepoint: At the end of the study
Secondary Outcome Measures
NameTimeMethod
1. Equation for the relationship between MAPSE and left ventricular ejection fraction <br/ ><br>2. Mean/Median time taken to measure MAPSE and left ventricular ejection fraction by modified Simpson’s method which will be compared using paired t-test or Wilcoxon <br/ ><br>Matched-Pairs Signed Ranks Test <br/ ><br>3. Comparison of ejection fraction from our equation, equation given my Matos et al <br/ ><br>and modified Simpson’s method using ANOVA test or Friedman test <br/ ><br>4. Validation of derived equation by calculating bias and precision as compared to the other two methods using Bland Altman analysis. <br/ ><br>5. Cutoff value of MAPSE to predict low left ventricular ejection fraction using receiver operating characteristic (ROC) curve analysis.Timepoint: At the end of the study
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