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A research for the application of pregabalin for anesthesia and interaction of pregabalin and anesthetic agent

Not Applicable
Conditions
condition which needs operation under anesthesia
Registration Number
JPRN-UMIN000015674
Lead Sponsor
Faculty of Dental Science, Kyushu University, Department of Dental Anesthesiology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
10
Inclusion Criteria

Not provided

Exclusion Criteria

Volunteers were excluded from recruitment if they were allergic to egg, soy and milk, allergic to any antibiotics or painkiller, chronic neuralgia patients, taking any GABA derivatives, or had dental disease that might cause severe pain

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood concentration of propofol to acheive the sufficient sedative level during intravenous sedation
Secondary Outcome Measures
NameTimeMethod
Circulation and respiration dynamics during intravenous sedation, perioperative analgesic effect, first propofol injection-induced pain and side effects at 30 minutes and 1hour after pregabalin administration, and 30 minutes. 1 hour and 5 hour after the intravenous sedation end.
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